Relevant studies and research about smart drugs and nootropics
Scientific Resources on Nutrition, Cognition & Brain Supplements
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ACADEMIC RESEARCH
- A controlled trial of vitamin-mineral supplementation: Effects of intelligence and performance (study in children).
http://www.sciencedirect.com/science/article/pii/019188699190287L
A triple-blind placebo-controlled design capable of determining whether supplements could produce significant gains in standardized validated indices of intelligence/performance. Results showed highly significant improvements in I.Q with the 100% RDA group showing an (average) 3.7 point IQ increase, and one-third of the cohort showing a 10 point IQ jump. The 200% RDA group showed lower improvements, similar to the 50% RDA group. - Micronutrient Deficiencies and Cognitive Functioning
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140638/ - Brain foods: the effects of nutrients on brain function
Nature Reviews Neuroscience 9, 568-578 (July 2008) | doi:10.1038/nrn2421
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805706/ - Nutrition and its effects on Academic Performance. How can our schools improve? https://www.nmu.edu/sites/DrupalEducation/files/UserFiles/Files/Pre-Drupal/SiteSections/Students/GradPapers/Projects/Ross_Amy_MP.pdf
- Effect of a 12-mo micronutrient intervention on learning and memory (study in children)
https://www.ncbi.nlm.nih.gov/pubmed/17921387/ - University of Aberdeen – Research Areas: Linking Nutrition to Cognition
http://www.abdn.ac.uk/clsm/graduate/research-areas/nutrition-cognition.php
Smart Drugs/Brain Enhancers, Nootropics, and Cognitive Enhancers
- Wikipedia page on ‘smart drugs’, nootropics and cognitive enhancers
https://en.wikipedia.org/wiki/Nootropic#Use_by_students
- Towards responsible use of cognitive-enhancing drugs by the healthy.
Nature (Scientific Journal) 456, 702-705 (11 December 2008) | doi:10.1038/456702a;
http://www.nature.com/nature/journal/v456/n7223/full/456702a.html
- ‘Use of ‘smart drugs’ on the rise’. Nature, (05 July 2018)
https://www.nature.com/articles/d41586-018-05599-8
- No Evidence of Dehydration with Moderate Daily Coffee Intake: A Counterbalanced Cross-Over Study in a Free-Living Population
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886980/
- De Moreno, J. (2003): ‘Cognitive improvement in mild to moderate Alzheimer’s dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial’. Clinical Therapeutics, 2003 Jan;25(1):178-93, PMID: 12637119
- 6Roodenrys, S., Booth, D., Bulzomi, S., Phipps, A., Micallef, C., and Smoker, J. (2002): ‘Chronic effects of Brahmi (Bacopa monnieri) on human memory’. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology, 2002 Aug;27(2):279-81, PMID: 12093601
- 2Di Perri, R., Coppola, G., Ambrosio, LA., Grasso, A., Puca, FM., and Rizzo, M. (1991): ‘A multicentre trial to evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia’. Journal of International Medical Research, 1991 Jul-Aug;19(4):330-41. PMID: 1916007
- 3Sun, QQ., Xu, SS., Pan, JL., Guo, HM., and Cao, WQ. (1999): ‘huperzine-A capsules enhance memory and learning performance in 34 pairs of matched adolescent students’. Zhongguo Yao Li Xue Bao. Acta Pharmacologica Sinica, 1999 JUl;20(7):601-3, PMID: 10678121
- 4Xu, SS., Gao, ZX., Weng, Z., Du, ZM., Xu, WA., Yang, JS., Zhang, ML., Tong, ZH., Fang, YS., and Chai, XS. (1995): ‘Efficacy of tablet huperzine-A on memory, cognition, and behaviour in Alzheimer’s disease’. Zhongguo Yao Li Xue Bao. Acta Pharmacologica Sinica, 1995 Sep;16(5):391-5, PMID: 8701750
- 5Morgan, A., and Stevens, J. (2010): ‘Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial’. Journal of Alternative and Complementary Medicine, 2010 JUl;16(7):753-9. doi: 10.1089/acm.2009.0342, PMID: 20590480
- 7Calabrese, C., Gregory, WL., Leo, M., Kraemer, D., Bone, K., and Oken, B. (2008): ‘effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial’. Journal of Alternative and Complementary Medicine, 2008 Jul;14(6):707-13. doi: 10.1089/acm.2008.0018, PMID 18611150
- 8Kennedy, DO., Jackson, PA., Forster, J., Khan, J., Grothe, T., Perrinjaquet-Moccetti, T., and Haskell-Ramsay, CF. (2015): ‘Acute effects of wild green-oat (Avena sativa) extract on cognitive function in middle-aged adults: A double-blind, placebo-controlled, within-subjects trial’. Nutritional Neuroscience, 2015 Nov 30, PMID: 26618715
- 9Berry, NM., Robinson, MJ., Bryan, J., Buckley, JD., Murphy, KJ., and Howe, PR. (2011): ‘Acute effects of an Avena sativa herb extract on responses to the Stroop Color-Word test’. Journal of Alternative and Complementary Medicine, 2011 Jul;17(7):635-7. doi: 10.1089/acm.2010.0450, PMID: 21711204
- 10Park, SK., Jung, IC., Lee, WK., Lee, YS., Park, HK,, Go, HJ., Kim, K., Lim, NK., Hong, JT., Ly, SY., Rho, SS. (2011): ‘A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study’. Journal of Medicinal Food, 2011 Apr;14(4):334-43. doi: 10.1089/jmf.2009.1374. Epub 2011 Feb 8, PMID: 21303262
- 11Steenburgen, L., Sellaro, R., Hommel, B., and Colzato, LS. (2015): ‘Tyrosine promotes cognitive flexibility: evidence from proactive vs. reactive control during task switching performance’. Neuropsychologia, 2015 Mar;69:50-5. doi: 10.1016/j.neuropsychologia.2015.01.022. Epub 2015 Jan 16. PMID: 25598314
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